• Effect of mindfulness-based interventions on people with prehypertension or hypertension: a systematic review and meta-analysis of randomized controlled trials

    Type de document Article de revue
    Auteur Qiongshan Chen
    Auteur Hui Liu
    Auteur Shizheng Du
    Résumé BACKGROUND: Hypertension and prehypertension have been widely recognized as the main contributors of global mortality. Evidence shows mindfulness-based interventions may reduce blood pressure and improve mental health. However, the effect of mindfulness-based interventions on blood pressure and mental health has not been fully understood. METHODS: Potential studies published before May 24th 2023 were identified by searching Embase, Ovid Emcare, PsycINFO, CINAHL, Web of Science, Cochrane, PubMed, China National Knowledge Infrastructure, Wanfang database, and VIP China Science. Additionally, two grey databases were searched: Mednar, WorldWideScience.org. The risk of bias in the included studies was assessed using the Cochrane Risk of Bias Assessment tool. The random-effects meta-analyses were conducted using Review Man 5.4 software and the key outcomes are presented as mean difference or standard mean difference and the 95% confidential interval. RESULTS: Searches returned 802 studies in total, of which 12 were included (N = 715). The duration of interventions was 8 weeks in 10 trials and 6 weeks in one trial. Pooled effect sizes indicated reductions in systolic blood pressure (MD = - 9.12, 95% CI [- 12.18, - 6.05], p < 0.001), diastolic blood pressure (MD = - 5.66, 95% CI [- 8.88, - 2.43], p < 0.001), anxiety (SMD = - 4.10; 95% CI [- 6.49, - 1.71], p < 0.001), depression (SMD = - 1.70, 95%CI [- 2.95, - 0.44], p < 0.001) and perceived stress (SMD = - 5.91, 95%CI [- 8.74, - 3.09], p < 0.001) at post-intervention. The findings from subgroup analyses are favorable for mindfulness-based interventions regardless of gender and baseline blood pressure with regard to BP reduction, with a more profound effect observed in participants with higher pre-intervention blood pressure. CONCLUSIONS: The results provide evidence for the positive role of mindfulness-based interventions in hypertension management. More large randomized control trials with sufficient statistical power and long-term follow-up are needed. TRIAL REGISTRATION: The protocol had been registered with Prospero on October 2nd 2021 (registration NO. CRD42021282504 ).
    Date 2024-02-14
    Langue eng
    Titre abrégé Effect of mindfulness-based interventions on people with prehypertension or hypertension
    Catalogue de bibl. PubMed
    Extra Number: 1 PMID: 38350849 PMCID: PMC10865530
    Volume 24
    Pages 104
    Publication BMC cardiovascular disorders
    DOI 10.1186/s12872-024-03746-w
    Numéro 1
    Abrév. de revue BMC Cardiovasc Disord
    ISSN 1471-2261
    Date d'ajout 23/03/2025 09:39:51
    Modifié le 23/03/2025 09:39:51

    Marqueurs :

    • Anxiety
    • Mindfulness
    • Depression
    • Adult
    • Humans
    • Middle Aged
    • Female
    • Male
    • Aged
    • Randomized Controlled Trials as Topic
    • Treatment Outcome
    • Mental Health
    • Blood Pressure
    • Hypertension
    • Blood pressure
    • Prehypertension

    Pièces jointes

    • PubMed entry
    • Texte intégral
  • Response to Commentary: Effects of Transcendental Meditation on Blood Pressure: A Meta-analysis

    Type de document Article de revue
    Auteur Joanne Kraenzle Schneider
    Auteur Chuntana Reangsing
    Auteur Danny G. Willis
    Date 2023 Mar-Apr 01
    Langue eng
    Titre abrégé Response to Commentary
    Catalogue de bibl. PubMed
    Extra Number: 2 PMID: 36752759
    Volume 38
    Pages 115-116
    Publication The Journal of Cardiovascular Nursing
    DOI 10.1097/JCN.0000000000000967
    Numéro 2
    Abrév. de revue J Cardiovasc Nurs
    ISSN 1550-5049
    Date d'ajout 23/03/2025 09:39:44
    Modifié le 23/03/2025 09:39:44

    Marqueurs :

    • Meditation
    • Humans
    • Blood Pressure
    • Hypertension
    • Vital Signs

    Pièces jointes

    • PubMed entry
  • Only Small Effects of Mindfulness-Based Interventions on Biomarker Levels of Inflammation and Stress: A Preregistered Systematic Review and Two Three-Level Meta-Analyses

    Type de document Article de revue
    Auteur Jakob Grasmann
    Auteur Frederick Almenräder
    Auteur Martin Voracek
    Auteur Ulrich S. Tran
    Résumé Mindfulness-based interventions (MBIs) have a positive effect on biomarkers of inflammation and stress in patients with psychiatric disorders and physical illnesses. Regarding subclinical populations, results are less clear. The present meta-analysis addressed the effects of MBIs on biomarkers in psychiatric populations and among healthy, stressed, and at-risk populations. All available biomarker data were investigated with a comprehensive approach, using two three-level meta-analyses. Pre-post changes in biomarker levels within treatment groups (k = 40 studies, total N = 1441) and treatment effects compared to control group effects, using only RCT data (k = 32, total N = 2880), were of similar magnitude, Hedges g = -0.15 (95% CI = [-0.23, -0.06], p < 0.001) and g = -0.11 (95% CI = [-0.23, 0.001], p = 0.053). Effects increased in magnitude when including available follow-up data but did not differ between type of sample, MBI, biomarker, and control group or duration of the MBI. This suggests that MBIs may ameliorate biomarker levels in both psychiatric and subclinical populations to a small extent. However, low study quality and evidence of publication bias may have impacted on the results. More large and preregistered studies are still needed in this field of research.
    Date 2023-02-23
    Langue eng
    Titre abrégé Only Small Effects of Mindfulness-Based Interventions on Biomarker Levels of Inflammation and Stress
    Catalogue de bibl. PubMed
    Extra Number: 5 PMID: 36901875 PMCID: PMC10003032
    Volume 24
    Pages 4445
    Publication International Journal of Molecular Sciences
    DOI 10.3390/ijms24054445
    Numéro 5
    Abrév. de revue Int J Mol Sci
    ISSN 1422-0067
    Date d'ajout 23/03/2025 09:39:46
    Modifié le 23/03/2025 09:39:46

    Marqueurs :

    • Mindfulness
    • mindfulness
    • Humans
    • Biomarkers
    • three-level meta-analysis
    • C-reactive protein
    • MBIs
    • Inflammation
    • Health Status
    • Mental Disorders
    • cortisol
    • biomarkers of inflammation and stress
    • interleukin

    Pièces jointes

    • PubMed entry
    • Texte intégral
  • Effects of mindfulness-based interventions on anthropometric outcomes: A systematic review and meta-analysis

    Type de document Article de revue
    Auteur Tsui-Sui Annie Kao
    Auteur Jiying Ling
    Auteur Mohammed Alanazi
    Auteur Ahmed Atwa
    Auteur Wachira Suriyawong
    Résumé BACKGROUND AND OBJECTIVES: The effects of mindfulness-based interventions (MBIs) on anthropometrics remain obscure. This review quantitatively synthesizes the effects of MBIs on decreasing body mass index (BMI), waist circumference (WC), weight, and percent body fat (%BF). METHODS: Seven databases, including CINAHL Plus with Full Text, PubMed, PsycINFO, Cochrane, Web of Science Core Collection, Embase, and Sociological Abstracts were searched; studies with a comparison group were selected. Random-effects models were then applied to estimate the pooled effects (Hedge's g), while exploratory moderation analyses with mixed-effects models were performed to explore potential moderators of MBIs on anthropometrics. RESULTS: The pooled effect size was -0.36 (p < .001) on BMI, -0.52 (p < .001) on WC, -1.20 (p < .004) on weight loss, and -0.43 (p = .389) on %BF. The long-term effects from baseline to follow-up and from post-intervention to follow-up were sustained on BMI (-0.37, p = .027; -.24, p = .065) and weight loss (-1.91, p = .027; -0.74, p = .011) respectively. For weight loss, adding mindful movement had greater effects than those without (-2.65 vs -0.39, p < .001). CONCLUSION: Our findings support the short-term MBI effects on BMI reduction, WC, weight, and %BF, and long-term effects on reducing BMI and weight. Future efforts should focus on sustaining effects on reducing WC and %BF.
    Date 2023
    Langue eng
    Titre abrégé Effects of mindfulness-based interventions on anthropometric outcomes
    Catalogue de bibl. PubMed
    Extra Number: 3 PMID: 37211464
    Volume 17
    Pages 175-183
    Publication Obesity Research & Clinical Practice
    DOI 10.1016/j.orcp.2023.05.006
    Numéro 3
    Abrév. de revue Obes Res Clin Pract
    ISSN 1871-403X
    Date d'ajout 23/03/2025 09:39:48
    Modifié le 23/03/2025 09:39:48

    Marqueurs :

    • Mindfulness
    • Humans
    • Weight Loss
    • Body Mass Index
    • Waist Circumference
    • Stress management
    • Healthy lifestyle
    • Obesity prevention
    • Weight reduction
    • Adipose Tissue

    Pièces jointes

    • PubMed entry
  • Mindfulness-Based Movement Intervention to Improve Sleep Quality: A Meta-Analysis and Moderator Analysis of Randomized Clinical Trials

    Type de document Article de revue
    Auteur Jiayi Yang
    Auteur Yan Du
    Auteur Haoran Shen
    Auteur Shujie Ren
    Auteur Zhiyuan Liu
    Auteur Danni Zheng
    Auteur Qingqing Shi
    Auteur Youfa Li
    Auteur Gao-Xia Wei
    Résumé (1) Background: Given that the most effective dose, optimal type, and most beneficial population for improving sleep with mindfulness-based movement (MBM) remains unknown, we conducted a systematic review and meta-analysis with moderator analysis of randomized controlled trials (RCTs) to assess these effects. (2) Methods: Three electronic databases (PubMed, Web of Science, and EBSCO) were systematically searched for RCTs published through August 2021 for analysis. The risk of bias of the included studies was assessed with Review Manager 5.3, and the meta-analysis was performed in Stata 16.0. (3) Results: A meta-analysis of 61 RCTs with 2697 participants showed that MBM significantly improved sleep quality compared to controls (SMD = −0.794; 95% CI: −0.794 to −0.994, p < 0.001, I2 = 90.7%). Moderator analysis showed that a long-term MBM (SMD = −0.829; 95% CI: 0.945 to 0.712; p < 0.001) had a larger effect size on sleep than a short-term MBM (SMD = −0.714; 95% CI: 0.784 to 0.644; p < 0.001). Practicing at least twice per week (SMD = −0.793; 95% CI: −0.868 to −0.718; p < 0.001) was more effective compared to practicing once per week (SMD = −0.687; 95% CI: −0.804 to −0.570; p < 0.001). Studies with a total intervention time of more than 24 h also revealed better sleep quality improvement (SMD = −0.759; 95% CI: −0.865 to −0.653; p < 0.001). In addition, the healthy population and older adults gained more from MBM than the patients and younger adults. (4) Conclusions: MBM can effectively improve subjective sleep quality, and the optimal intervention dose of MBM can be utilized in future intervention studies to treat or improve sleep disturbance (MBM more than twice a week for more than three months, with a total intervention time of more than 24 h).
    Date 2022-08-18
    Langue eng
    Titre abrégé Mindfulness-Based Movement Intervention to Improve Sleep Quality
    Catalogue de bibl. PubMed
    Extra Number: 16 PMID: 36011918 PMCID: PMC9408303
    Volume 19
    Pages 10284
    Publication International Journal of Environmental Research and Public Health
    DOI 10.3390/ijerph191610284
    Numéro 16
    Abrév. de revue Int J Environ Res Public Health
    ISSN 1660-4601
    Date d'ajout 23/03/2025 09:39:36
    Modifié le 23/03/2025 09:39:36

    Marqueurs :

    • Mindfulness
    • Humans
    • meta-analysis
    • Aged
    • sleep quality
    • Randomized Controlled Trials as Topic
    • Sleep Quality
    • randomized controlled trials
    • mindfulness-based movement
    • Sleep Wake Disorders
    • Health Status

    Pièces jointes

    • PubMed entry
    • Texte intégral
  • The effects of body scan meditation: A systematic review and meta-analysis

    Type de document Article de revue
    Auteur Ruochen Gan
    Auteur Liuyi Zhang
    Auteur Shulin Chen
    Résumé Standardized mindfulness-based stress reduction (MBSR) has been proved to be effective across many populations while the time commitment for the standardized intervention leads to high attrition rate. To address the problem, there has been a growing interest in conducting a single component of MBSR such as body scan. However, the impact of a sole mindfulness-based intervention (MBI) remains unclear. The aim of this study was to investigate the effects of body scan meditation. A search of databases, including PubMed, Embase, EBSCO, Cochrance, Proquest Dissertations, and Theses, was conducted for randomized controlled trials with no population restriction. Fourteen independent articles were identified and outcomes were divided into seven categories. A meta-analysis with robust variance estimation was conducted separately for different outcome categories. Body scan only had small effect on mindfulness when compared with passive control (Hedge's g = .268, 95% CI = [0.032, 0.504], p < .05). The attrition rate of long-term interventions was low. The quality of these studies was low. There was high heterogeneity across studies. A sole body scan meditation is not effective enough to improve health-related outcomes.
    Date 2022-08
    Langue eng
    Titre abrégé The effects of body scan meditation
    Catalogue de bibl. PubMed
    URL https://pubmed.ncbi.nlm.nih.gov/35538557/
    Extra Number: 3 PMID: 35538557
    Volume 14
    Pages 1062-1080
    Publication Applied Psychology. Health and Well-Being
    DOI 10.1111/aphw.12366
    Numéro 3
    Abrév. de revue Appl Psychol Health Well Being
    ISSN 1758-0854
    Date d'ajout 23/03/2025 09:39:34
    Modifié le 23/03/2025 09:39:34

    Marqueurs :

    • Mindfulness
    • mindfulness
    • Meditation
    • Humans
    • meta-analysis
    • systematic review
    • body scan

    Pièces jointes

    • PubMed entry
  • The effect of mindfulness-based interventions on immunity-related biomarkers: a comprehensive meta-analysis of randomised controlled trials

    Type de document Article de revue
    Auteur Thomas J. Dunn
    Auteur Mirena Dimolareva
    Résumé One proposed pathway that mindfulness-based interventions (MBIs) may offer a salutogenic effect on somatic disorders is by enhancing immune function. As such, we conducted a meta-analysis of randomised controlled trials examining the effect of MBIs at post-intervention and follow-up for six immune-related biomarkers, including CD4+ cells, C-reactive protein, interleukin-6, nuclear factor-κB, telomere length, and telomerase activity. Potential studies were identified by searching ScienceDirect, Web of Science, Academic Search Complete, AMED, MEDLINE, PsycARTICLES, and PsycINFO. Searches returned 1959 studies, of which 48 (70 effects) were included (N = 4683). Pooled effect sizes indicated a reduction in C-reactive protein (SMCD = -.14, 95% CI [-.26 - -.01]) and interleukin-6 (SMCD = -.35, 95% CI [-.67 - -.03]), and an increase in CD4+ (SMCD = .09, 95% CI [-.05 - .22]), telomere length (SMCD = .12, 95% CI [.00 - .24]) and telomerase activity (SMCD = .81, 95% CI [.17 - 1.46]) at post-intervention. At follow-up, results showed a reduction in interleukin-6 (SMCD = -.13, 95% CI [-.29 - .03]) and C-reactive protein (SMCD = -.39, 95% CI [-.68 - -.10]) and increase in CD4+ (SMCD = .22, 95% CI [-.08 - .52]). Meta-regression results showed that some heterogeneity in effect size could be accounted for by intervention dosage, study population, and study design. Our findings quantify MBIs' potential for improving immune function and thus impacting somatic disorders.
    Date 2022-03
    Langue eng
    Titre abrégé The effect of mindfulness-based interventions on immunity-related biomarkers
    Catalogue de bibl. PubMed
    URL https://pubmed.ncbi.nlm.nih.gov/35078038/
    Extra PMID: 35078038
    Volume 92
    Pages 102124
    Publication Clinical Psychology Review
    DOI 10.1016/j.cpr.2022.102124
    Abrév. de revue Clin Psychol Rev
    ISSN 1873-7811
    Date d'ajout 23/03/2025 09:39:32
    Modifié le 23/03/2025 09:39:32

    Marqueurs :

    • MBSR
    • Mindfulness
    • Humans
    • Randomized Controlled Trials as Topic
    • MBCT
    • Biomarkers
    • C-reactive protein
    • CD4
    • CRP
    • IL-6
    • Immune function
    • Immunity
    • Inflammatory
    • Interleukin
    • MBI
    • Mindfulness-based
    • Telomeres
    • C-Reactive Protein
    • Interleukin-6
    • Telomerase

    Pièces jointes

    • PubMed entry
  • The Effects of Mindfulness and Meditation on Vagally Mediated Heart Rate Variability: A Meta-Analysis

    Type de document Article de revue
    Auteur Lydia Brown
    Auteur Alora A. Rando
    Auteur Kristina Eichel
    Auteur Nicholas T. Van Dam
    Auteur Christopher M. Celano
    Auteur Jeff C. Huffman
    Auteur Meg E. Morris
    Résumé OBJECTIVE: Heart rate variability (HRV) is a marker of autonomic nervous system function associated with both physical and mental health. Many studies have suggested that mindfulness and meditation-based interventions (MBIs) are associated with improvements in HRV, but findings are mixed, and to date, no comprehensive meta-analysis has synthesized results. METHODS: Systematic literature searches were conducted using PsycINFO, Embase, Medline, CINAHL, ERIC, and Scopus to identify randomized controlled trials (RCTs) investigating the effects of predominantly seated MBIs on resting-state vagally mediated HRV. Risk of bias was judged using the Cochrane Risk of Bias tool. RESULTS: Nineteen RCTs met the criteria for inclusion in the meta-analysis. Random-effects meta-analysis found that MBIs were not efficacious in increasing vagally mediated resting-state HRV relative to control conditions (Hedges g = 0.38, 95% confidence interval [CI] = -0.014 to 0.77). When removing an outlier (g = 3.22), the effect size was reduced, CI narrowed, and findings remained nonsignificant (g = 0.19, 95% CI = -0.02 to 0.39). High heterogeneity in results (I2 = 89.12%) could not be explained by a priori-determined moderators including intervention duration, study setting, and control type. CONCLUSIONS: There is currently insufficient evidence to indicate that MBIs lead to improvements in vagally mediated HRV over control conditions. Future large, well-designed RCTs with low risk of methodological bias could help add to the current evidence to elucidate any role MBIs might play in impacting HRV.
    Date 2021 Jul-Aug 01
    Langue eng
    Titre abrégé The Effects of Mindfulness and Meditation on Vagally Mediated Heart Rate Variability
    Catalogue de bibl. PubMed
    Extra Number: 6 PMID: 33395216 PMCID: PMC8243562
    Volume 83
    Pages 631-640
    Publication Psychosomatic Medicine
    DOI 10.1097/PSY.0000000000000900
    Numéro 6
    Abrév. de revue Psychosom Med
    ISSN 1534-7796
    Date d'ajout 23/03/2025 09:39:23
    Modifié le 23/03/2025 09:39:23

    Marqueurs :

    • Mindfulness
    • Meditation
    • Humans
    • Mental Health
    • Heart Rate
    • Research Design

    Pièces jointes

    • PubMed entry
    • Version acceptée
  • Effectiveness of mindfulness-based interventions on quality of life and menopausal symptoms in menopausal women: A meta-analysis

    Type de document Article de revue
    Auteur Tsai-Ling Chen
    Auteur Shu-Chen Chang
    Auteur Chin-Yi Huang
    Auteur Hsiu-Hung Wang
    Résumé OBJECTIVE: Menopause is a normal physiological process experienced by women, but it is often accompanied by physical and emotional symptoms that may negatively affect quality of life. This meta-analysis aimed to evaluate the effectiveness of mindfulness-based interventions on quality of life and menopausal symptoms by examining randomized controlled trials. METHODS: A systematic search was conducted across six electronic databases to collect relevant articles published up to June 30, 2020. The articles' quality was assessed using the modified Jadad scale. We performed a meta-analysis with Review Manager 5.3, calculating 95% confidence intervals and standardized mean differences, and conducted sensitivity analyses. RESULTS: The meta-analysis of five randomized controlled trials included 475 participants. The results indicated that the mindfulness-based intervention groups showed significant improvements in total quality of life and vasomotor and physical quality of life, compared to control groups (standardized mean differences range: from -0.48 to -0.68, all ps < 0.05). After the sensitivity analyses, evidence of heterogeneity remained. Insufficient data prevented conducting a meta-analysis with the sexual subscale of MENQOL or on vasomotor symptoms of menopause. CONCLUSION: For menopausal women, mindfulness-based interventions may improve quality of life (except for psychological and sexual subscales). However, there is insufficient evidence to analyze whether such interventions can reduce vasomotor-related menopausal symptoms. Although heterogeneity should be carefully assessed, mindfulness-based interventions may be a novel approach for improving women's overall quality of life during menopause. However, further research is needed to verify these effects.
    Date 2021-08
    Langue eng
    Titre abrégé Effectiveness of mindfulness-based interventions on quality of life and menopausal symptoms in menopausal women
    Catalogue de bibl. PubMed
    URL https://pubmed.ncbi.nlm.nih.gov/34034137/
    Extra PMID: 34034137
    Volume 147
    Pages 110515
    Publication Journal of Psychosomatic Research
    DOI 10.1016/j.jpsychores.2021.110515
    Abrév. de revue J Psychosom Res
    ISSN 1879-1360
    Date d'ajout 23/03/2025 09:39:29
    Modifié le 23/03/2025 09:39:29

    Marqueurs :

    • Mindfulness
    • Humans
    • Meta-analysis
    • Mindfulness-based interventions
    • Female
    • Quality of Life
    • Quality of life
    • Menopausal symptoms
    • Menopause

    Pièces jointes

    • PubMed entry
  • Meditation interventions efficiently reduce cortisol levels of at-risk samples: a meta-analysis

    Type de document Article de revue
    Auteur Adam Koncz
    Auteur Zsolt Demetrovics
    Auteur Zsofia K. Takacs
    Résumé Previous meta-analytic results showed beneficial effects of meditation interventions for cortisol levels. In the present meta-analysis we tested whether effects are larger for those who might be in need of such stress reduction programs due to a risk for elevated cortisol levels as compared to no-risk samples. We included RCTs that measured change in cortisol levels. Based on 10 studies using blood samples meditation interventions had a significant, medium effect from pre-to post-test compared to the control group. Upon closer inspection, this effect was only present for at-risk samples, that is, patients with a somatic illness. In the 21 studies using saliva samples the effect was small and not significant, but there was a marginally significant effect for groups living in stressful life situations. This pattern may suggest that that meditation interventions are most beneficial for at-risk populations. These interventions might provide people with strategies of stress management that can contribute to well-being. Preliminary results suggest that benefits of meditation interventions might not fade with time.
    Date 2021-03
    Langue eng
    Titre abrégé Meditation interventions efficiently reduce cortisol levels of at-risk samples
    Catalogue de bibl. PubMed
    Extra Number: 1 PMID: 32635830
    Volume 15
    Pages 56-84
    Publication Health Psychology Review
    DOI 10.1080/17437199.2020.1760727
    Numéro 1
    Abrév. de revue Health Psychol Rev
    ISSN 1743-7202
    Date d'ajout 23/03/2025 09:39:18
    Modifié le 23/03/2025 09:39:18

    Marqueurs :

    • Meditation
    • Humans
    • meta-analysis
    • meditation
    • Stress, Psychological
    • Hydrocortisone
    • Risk Factors
    • Saliva
    • stress management
    • cortisol
    • at-risk samples
    • long-term effect

    Pièces jointes

    • PubMed entry
    • Texte intégral